Next-Level Preventive Testing: Thoughtfully Curated Science
At Portfolio Health we go beyond routine screenings.
Traditional medicine waits for problems to appear—-we aim to prevent them entirely.Our testing panels are meticulously curated to identify early risks, optimize treatments, and fine-tune your health strategy for the decades ahead, all while offering the best value possible.
Many longevity and concierge practices treat this kind of
advanced testing as a trade secret, but I believe that knowledge should be shared. The real secret of great care is not the science, but a seamless, patient-first experience that makes it effortless for you.
- LDL Particle Size** → Small LDL is more dangerous than large
Cardiovascular & Metabolic Health
- ApoB → Better estimate of harmful cholesterol
- LDL Particle Size** → Small LDL is more dangerous than large
- Myeloperoxidase (MPO) → Marker of vascular inflammation
- Lipoprotein(a) (Lp(a)) → Genetic risk for heart disease
- Oxidized LDL → Tracks damage due to reactive oxygen species and an inflammatory LDL.
- Myeloperoxidase (MPO) → Marker of vascular inflammation
- **Homocysteine** → Elevated levels increase stroke and clot risk
- Lp-PLA2 → Predictor of plaque rupture and heart attack risk
- **hsCRP** → General inflammation marker, linked to heart disease
- **Homocysteine** → Elevated levels increase stroke and clot risk
- **Uric Acid** → Excess levels linked to gout and metabolic dysfunction
- **Fibrinogen** → Elevated levels signal clotting risk
- **APOE** → Alzheimer’s risk and response to fats
### **Genetics & Disease Risk**
- **BRCA1 & BRCA2** → Inherited breast/ovarian cancer risk
- **APOE** → Alzheimer’s risk and response to fats
- **HLA-DQ2
/
$DQ8** → Determines celiac disease risk
- **HLA-B27** → Linked to autoimmune arthritis
- **HLA-DR4** → Strong predictor of severe rheumatoid arthritis
- **HLA-DQ2
/
$DQ8** → Determines celiac disease risk
- **PALB2** → High-risk breast cancer gene
- **HLA-DR15** → Most significant genetic risk factor for multiple sclerosis
- **CHEK2 & ATM** → Moderate genetic risk for breast cancer
- **PALB2** → High-risk breast cancer gene
- **CYP2D6** → Affects metabolism of antidepressants and opioids
### **Pharmacogenetics (Personalized Medication Response)**
- **CYP2C19** → Determines response to Plavix (clopidogrel)
- **CYP2D6** → Affects metabolism of antidepressants and opioids
- **HLA-B*15:02 & HLA-A*31:01** → Warns of severe reaction to carbamazepine (seizure & nerve pain med)
- **SLCO1B1** → Predicts statin side effects
- **HLA-B*57:01** → Prevents life-threatening reaction to abacavir (HIV med)
- **HLA-B*15:02 & HLA-A*31:01** → Warns of severe reaction to carbamazepine (seizure & nerve pain med)
- **Leptin & Adiponectin** → Markers of metabolic efficiency
### **Hormonal & Metabolic Optimization**
- **Insulin & HOMA-IR** → Early warning for insulin resistance
- **Leptin & Adiponectin** → Markers of metabolic efficiency
- **TSH & Free T4** → Thyroid health
- **Testosterone (Free & Total), Estradiol, FSH, LH, Prolactin, DHEA-S** → Hormone balance indicators
- **Cortisol** → Stress and adrenal function
- **TSH & Free T4** → Thyroid health
- **GBA & LRRK2** → Genetic Parkinson’s disease risk
### **Neurological & Cognitive Health**
- **AD Detect (Amyloid Beta & p-Tau217)** → Early Alzheimer’s detection
- **GBA & LRRK2** → Genetic Parkinson’s disease risk
- **C9orf72 & SOD1** → Genetic ALS risk
- **GRN & MAPT** → Frontotemporal dementia risk
- **EBV IgG** → Epstein-Barr virus history (linked to MS & lymphoma)
### **Infectious Disease Exposure & Immunity**
- **Varicella-Zoster IgG** → Determines shingles risk
- **EBV IgG** → Epstein-Barr virus history (linked to MS & lymphoma)
- **Measles, Mumps, Rubella (MMR) IgG** → Immunity check
- **CMV IgG** → Immune system aging marker
- **Hepatitis B Surface Antibody** → Confirms vaccine protection
- **Measles, Mumps, Rubella (MMR) IgG** → Immunity check
- **HPV High-Risk Strain Test** → Cervical & throat cancer risk
- **SARS-CoV-2 Spike IgG** → COVID-19 immunity post-infection or vaccination
- **HSV-1 & HSV-2 IgG** → Oral and genital herpes status
- **HPV High-Risk Strain Test** → Cervical & throat cancer risk
- **H. pylori IgG** → Stomach cancer and ulcer risk
- **MT-RNR1** → Warns of antibiotic-induced deafness
### **Hearing & Vision Loss Prevention**
- **GJB2 & GJB6** → Adult-onset hearing loss risk
- **MT-RNR1** → Warns of antibiotic-induced deafness
- **CFH & ARMS2** → Genetic risk for macular degeneration
- **OPTN & MYOC** → Open-angle glaucoma risk
### **Why This Matters**
Every test we offer has been chosen because it’s **clinically meaningful, scientifically validated, and actionable**. We don’t believe in over-testing—we believe in **testing with purpose**.
**The result?** More insights. More control. More years of vibrant health.
Most practices keep this level of testing **behind closed doors**—but I believe the best healthcare is **transparent, personalized, and designed around you.**
### **Take Control of Your Future Health**
This level of care isn’t about fixing problems **after they happen**—it’s about making sure they **never do**.
If you’re ready to get ahead of your health and **optimize for longevity, vitality, and peak performance**, we’re here to make it effortless.
Let’s redefine what **proactive, intelligent healthcare** can be—together.